ea0063gp213 | Gestational and Type 1 Diabetes | ECE2019
Popova Polina
, Vasileva Liudmila
, Tkachuck Alexandra
, Puzanov Maxim
, Golovkin Alexey
, Bolotko Yana
, Pustozerov Eugenii
, Gerasimov Andrey
, Zazerskaya Irina
, Dmitrieva Renata
, Kostareva Anna
, Grineva Elena
Background: Understanding the mechanism whereby the intrauterine hyperglycemia in women with gestational diabetes mellitus (GDM) affects the offspring predisposition to metabolic and cardiovascular diseases may help prevent their intergenerational transmission. Our aim was to study the effect of the degree and duration of maternal hyperglycemia on the level of expression of genes associated with cardio-metabolic diseases in human umbilical vein endothelial cells (HUVECs)...